A recent high-risk exposure (within 72 hours)


A course of non-occupational post exposure prophylaxis (nPEP) may be required if a patient is on daily PrEP, or on-demand PrEP and had a recent high-risk exposure (within 72 hours) but only if they did not take PrEP during those days. This nPEP may need to consist of a three-drug regimen, depending on the nature of the exposure. See section on nPEP and PrEP for management of such cases.

The Therapeutic Goods Administration (TGA) has not approved this regimen in Australia.